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Talks Announced: Register for the Nanion User Meeting!
Register today for our annual user meeting! 19th - 20th October 2022 
We are delighted to announce that we will hold our Annual User Meeting 2022 as a live event on 19th - 20th October 2022. Join us for 2 days of outstanding talks, product demos, SyncroPatch 384 workshop, posters, networking and much more! 

 
Click here to view the agenda and register!
It's coming home: The SyncroPatch 384 is installed in Göttingen, the birthplace of patch clamp! 

We are pleased to announce that the SyncroPatch 384 has been installed at the MBExC Cluster of Excellence at the University Medical Centre Göttingen (UMG) to advance investigation into the electrical activity of isolated cardiomyocytes and neurons.

Read the press release here!
  NEWS    
Job Exchange, Publication Highlights

Spotlight Publications
Patchliner

Anticancer effect of verteporfin on non-small cell lung cancer via downregulation of ANO1
Jeong S.B., et al., Biomedicine & Pharmacotherapy (2022)
Download Here
Further reading?
We have summarized all publications from 2022 - Present
Publications 2022 - Present

Meet Us - The Ion Channel Regulation Conference

Jobs for Electrophysiologists

Find available jobs within Academia, Industry, and at Nanion!

Patchliner Stories - University of Leeds

Learn more about the 2nd Patchliner ever made and going strong after 15 years!
Read More

Win an iPad or $400 Gift Card!

Review a product between August 1st - September 30th, 2022 to enter for a chance to win!

Nanion embraces Diversity

Meet Andre Bazzone, Senior Scientist / Principal Investigator
Read More Here

Research Ins]i[ghts: Nanion’s Transporter Webinar Series 2022


Date: 08.09.2022
Time: 10AM EDT, 4PM CEST
Title: Functional characterization and substrate binding kinetics of the Na+ cotransporters SGLT1 and GAT1

Register Here

On-Demand Transporter Webinar


Date: 28.06.2022
Time: 10AM EDT, 4PM CEST
Title: Structures and mechanism of the plant PIN-FORMED auxin transporter

Watch Here

On-Demand Patch Clamp Webinar


Date: 14.07.2022
Time: 10AM EDT, 4PM CEST
Title: An in silico-in vitro pipeline for drug cardiotoxicity screening identifies ionic proarrhythmia mechanisms

Watch Here

Snapshot of the Month

Nanion celebrated 20 years of innovat]i[on with our fabulous colleagues (past and present), collaborators, customers, family and friends. 
  TOPIC   
TMEM16A and its role in cancer
TMEM16A: a novel drug target for NSCLC  

TMEM16A, also known as Anoctamin 1 (ANO1) is a calcium-activated chloride channel which has a broad functional spectrum in processes including trans-epithelial ion transport, olfaction, photo-transduction, smooth muscle contraction, nociception, cell proliferation and control of neuronal excitability. It is is overexpressed in non-small cell lung cancer (NSCLC), a major cause of cancer-related mortality and is a novel potential drug target for NSCLC. In a recent paper, researchers found that the anticancer mechanism of the compound verteporfin is caused via the down-regulation of ANO1. 

TMEM16A can be measured using automated patch clamp. Read more about activation of TMEM16A by internal perfusion of Ca2+ in this Application Note.

 
Visit our website for more Publications and Application Notes!
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