Study summaries and literature digests on clinical pharmacogenomics
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Greetings from the University of Florida Health Personalized Medicine Program! We hope you enjoy the Spring 2016 edition of SNPits, a newsletter committed to bringing you updates on clinical applications of pharmacogenomics research.

In the News

New IGNITE-SPARK Toolbox and website: Practical resources for implementing genomic medicine

The Implementing Genomics in Patient Care (IGNITE) Network has launched a redesigned website, including the IGNITE–SPARK Toolbox, an open online resource of peer-reviewed genomic medicine implementation tools for clinicians, researchers, educators, and patients. Explore the new website, download a resource from the Toolbox, or consider submitting a resource from your practice.

PharmGKB introduces new Cancer PGx portal

PharmGKB recently announced a new collection of cancer-related pharmacogenomics resources, including tables with direct links to genes important for cancer drug response both for pharmacodynamics and pharmacokinetics, to cancer drug pathways, particular cancers that have PGx data, types of toxicities common to cancer drugs, and external resources.

Study Summaries

Drug–drug and drug–gene interactions in patients undergoing PGx testing

As pharmacogenetic data are increasingly being incorporated into the patient care decision making process, additional information is needed to inform clinician strategies and priorities. An important step in obtaining these data...

TPMT genotyping: Decreased hematologic adverse events in IBD

Thiopurine agents such as 6-mercaptopurine or azathioprine are used in patients with inflammatory bowel disease (IBD) as well as some pediatric cancers (i.e., acute lymphoblastic leukemia, ALL). Although these agents can be effective for maintaining remission in IBD...

ACMG revises position statement on direct-to-consumer genetic testing

In response to increasing availability of genetic testing opportunities and consumer demand, the American College of Medical Genetics (ACMG) has updated its 2008 position statement on direct-to-consumer genetic testing...

Recent Literature


Browse more Cardiology articles.

Clinical Pharmacogenomics

Browse more Clinical Pharmacogenomics articles.


Browse more Hematology/Oncology articles.

Infectious Diseases

Browse more Infectious Diseases articles.

Pain Management

Browse more Pain Management articles.
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The UF Health Personalized Medicine Program is part of the UF Clinical and Translational Science Institute and has been funded to date by NIH grants U01 GM074492 and U01 HL105198 (as part of the TPP project in the NIH PGRN); NIH/NCATS UF CTSA UL1 TR000064; IGNITE Network grant U01 HG007269; and substantial institutional support from the University of Florida.

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